{"id":2,"date":"2017-09-26T08:08:51","date_gmt":"2017-09-26T08:08:51","guid":{"rendered":"https:\/\/demo.i3cdevelopers.ug\/usmr\/\/?page_id=2"},"modified":"2025-04-22T08:50:22","modified_gmt":"2025-04-22T08:50:22","slug":"about-us","status":"publish","type":"page","link":"https:\/\/www.muii.org.ug\/usmrc\/about-us\/","title":{"rendered":"About Us"},"content":{"rendered":"<section class=\"wpb-content-wrapper\"><p>[vc_row full_width=&#8221;stretch_row_content_no_spaces&#8221;][vc_column]\n\t\t\t<!-- START Mainsite REVOLUTION SLIDER 6.6.11 --><p class=\"rs-p-wp-fix\"><\/p>\n\t\t\t<rs-module-wrap id=\"rev_slider_1_1_wrapper\" data-source=\"gallery\" style=\"visibility:hidden;background:transparent;padding:0;margin:0px auto;margin-top:0;margin-bottom:0;\">\n\t\t\t\t<rs-module id=\"rev_slider_1_1\" style=\"\" data-version=\"6.6.11\">\n\t\t\t\t\t<rs-slides style=\"overflow: hidden; position: absolute;\">\n\t\t\t\t\t\t<rs-slide style=\"position: absolute;\" data-key=\"rs-12\" data-title=\"Slide\" data-thumb=\"\/\/www.muii.org.ug\/usmrc\/wp-content\/uploads\/2024\/09\/IMG-20240809-WA0053-100x50.jpg\" data-anim=\"ms:600;\" data-in=\"o:0;\" data-out=\"a:false;\">\n\t\t\t\t\t\t\t<img src=\"\/\/www.muii.org.ug\/usmrc\/wp-content\/plugins\/revslider\/public\/assets\/assets\/dummy.png\" alt=\"\" title=\"IMG-20240809-WA0053\" width=\"2560\" height=\"1920\" class=\"rev-slidebg tp-rs-img rs-lazyload\" data-lazyload=\"\/\/www.muii.org.ug\/usmrc\/wp-content\/uploads\/2024\/09\/IMG-20240809-WA0053.jpg\" data-no-retina>\n<!--\n\t\t\t\t\t\t\t--><rs-layer\n\t\t\t\t\t\t\t\tid=\"slider-1-slide-12-layer-1\" \n\t\t\t\t\t\t\t\tdata-type=\"text\"\n\t\t\t\t\t\t\t\tdata-color=\"#ffffff\"\n\t\t\t\t\t\t\t\tdata-rsp_ch=\"on\"\n\t\t\t\t\t\t\t\tdata-xy=\"y:c;yo:65px;\"\n\t\t\t\t\t\t\t\tdata-text=\"s:40;l:57;fw:200;a:inherit;\"\n\t\t\t\t\t\t\t\tdata-frame_0=\"o:1;\"\n\t\t\t\t\t\t\t\tdata-frame_0_sfx=\"se:blocktoright;\"\n\t\t\t\t\t\t\t\tdata-frame_1=\"e:power4.inOut;sp:2000;\"\n\t\t\t\t\t\t\t\tdata-frame_1_sfx=\"se:blocktoright;\"\n\t\t\t\t\t\t\t\tdata-frame_999=\"o:0;st:w;sR:7000;\"\n\t\t\t\t\t\t\t\tstyle=\"z-index:5;font-family:'Poppins';text-transform:uppercase;\"\n\t\t\t\t\t\t\t><div class=\"slider-caption-1 style=\"color:#fff;\">\n<div class=\"slider-title\" style=\"color:#fff;\">\n<strong><span style=\"color:#fff;\">Uganda Schistosomiasis<br> Multi-disciplinary<br> Research Center<\/span><\/strong><br \/>\n<\/div>\n\n<\/div> \n\t\t\t\t\t\t\t<\/rs-layer><!--\n-->\t\t\t\t\t\t<\/rs-slide>\n\t\t\t\t\t\t<rs-slide style=\"position: absolute;\" data-key=\"rs-11\" data-title=\"Slide\" data-thumb=\"\/\/www.muii.org.ug\/usmrc\/wp-content\/uploads\/2024\/04\/Malla-13-100x50.jpeg\" data-anim=\"ms:600;\" data-in=\"o:0;\" data-out=\"a:false;\">\n\t\t\t\t\t\t\t<img src=\"\/\/www.muii.org.ug\/usmrc\/wp-content\/plugins\/revslider\/public\/assets\/assets\/dummy.png\" alt=\"\" title=\"Malla 13\" width=\"1080\" height=\"810\" class=\"rev-slidebg tp-rs-img rs-lazyload\" data-lazyload=\"\/\/www.muii.org.ug\/usmrc\/wp-content\/uploads\/2024\/04\/Malla-13.jpeg\" data-no-retina>\n<!--\n\t\t\t\t\t\t\t--><rs-layer\n\t\t\t\t\t\t\t\tid=\"slider-1-slide-11-layer-1\" \n\t\t\t\t\t\t\t\tdata-type=\"text\"\n\t\t\t\t\t\t\t\tdata-color=\"#ffffff\"\n\t\t\t\t\t\t\t\tdata-rsp_ch=\"on\"\n\t\t\t\t\t\t\t\tdata-xy=\"y:c;yo:65px;\"\n\t\t\t\t\t\t\t\tdata-text=\"s:40;l:57;fw:200;a:inherit;\"\n\t\t\t\t\t\t\t\tdata-frame_0=\"o:1;\"\n\t\t\t\t\t\t\t\tdata-frame_0_sfx=\"se:blocktoright;\"\n\t\t\t\t\t\t\t\tdata-frame_1=\"e:power4.inOut;sp:2000;\"\n\t\t\t\t\t\t\t\tdata-frame_1_sfx=\"se:blocktoright;\"\n\t\t\t\t\t\t\t\tdata-frame_999=\"o:0;st:w;sR:7000;\"\n\t\t\t\t\t\t\t\tstyle=\"z-index:5;font-family:'Poppins';text-transform:uppercase;\"\n\t\t\t\t\t\t\t><div class=\"slider-caption-1 style=\"color:#fff;\">\n<div class=\"slider-title\" style=\"color:#fff;\">\n<strong><span style=\"color:#fff;\">Uganda Schistosomiasis<br> Multi-disciplinary<br> Research Center<\/span><\/strong><br \/>\n<\/div>\n<\/div> \n\t\t\t\t\t\t\t<\/rs-layer><!--\n-->\t\t\t\t\t\t<\/rs-slide>\n\t\t\t\t\t<\/rs-slides>\n\t\t\t\t\t<rs-static-layers><!--\n\t\t\t\t\t--><\/rs-static-layers>\n\t\t\t\t<\/rs-module>\n\t\t\t\t<script>\n\t\t\t\t\tsetREVStartSize({c: 'rev_slider_1_1',rl:[1240,1024,778,480],el:[550],gw:[1170],gh:[550],type:'standard',justify:'',layout:'fullwidth',mh:\"0\"});if (window.RS_MODULES!==undefined && window.RS_MODULES.modules!==undefined && window.RS_MODULES.modules[\"revslider11\"]!==undefined) {window.RS_MODULES.modules[\"revslider11\"].once = false;window.revapi1 = undefined;if (window.RS_MODULES.checkMinimal!==undefined) window.RS_MODULES.checkMinimal()}\n\t\t\t\t<\/script>\n\t\t\t<\/rs-module-wrap>\n\t\t\t<!-- END REVOLUTION SLIDER -->\n[\/vc_column][\/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_empty_space height=&#8221;40px&#8221;][vc_custom_heading text=&#8221;Background&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_empty_space height=&#8221;40px&#8221;][\/vc_column_inner][\/vc_row_inner][vc_row_inner gap=&#8221;15&#8243;][vc_column_inner width=&#8221;1\/2&#8243;][vc_empty_space height=&#8221;10px&#8221;]<ul class=\"iconlist iconlist iconlist-icon-small \"><li ><div class=\"iconlist-item-icon\"><i class=\"sl-check\"><\/i><span class=\"shapes\"><\/span><\/div><div class=\"iconlist-item-content\">Schistosomiasis is a major parasitic cause of global morbidity and mortality. Schistosoma mansoni (Sm) is highly prevalent in Uganda. In 2016-17, surveys estimated 25% of the population to be infected and 50% at risk. Most cases are found around the Great Lakes and River Nile.<\/div><\/li><li ><div class=\"iconlist-item-icon\"><i class=\"sl-check\"><\/i><span class=\"shapes\"><\/span><\/div><div class=\"iconlist-item-content\">The Ministry of Health\u2019s Vector Control Division (VCD), responsible for schistosomiasis control, has long been concerned about extreme disease severity among populations living beside Lake Albert and the Albert Nile in West and Northern Uganda (LA region), compared to those of the Lake Victoria (LV region) in Central and Eastern Uganda.<\/div><\/li><li ><div class=\"iconlist-item-icon\"><i class=\"sl-check\"><\/i><span class=\"shapes\"><\/span><\/div><div class=\"iconlist-item-content\">This is despite comparable high prevalence, infection intensity, and mass praziquantel treatment efforts in the two settings. To understand the mechanisms underlying this geographic difference in morbidity, we will directly compare representative, highly exposed populations in the two settings.<\/div><\/li><\/ul>[\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_empty_space height=&#8221;30px&#8221;][vc_single_image image=&#8221;2720&#8243; img_size=&#8221;640*480&#8243;][vc_empty_space height=&#8221;30px&#8221;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1688458395547{background-color: #e9eaee !important;}&#8221;][vc_column][vc_row_inner css=&#8221;.vc_custom_1688539340866{background-color: #e9eaee !important;}&#8221;][vc_column_inner width=&#8221;1\/3&#8243;][vc_empty_space height=&#8221;40px&#8221;][vc_custom_heading text=&#8221;Specific Aims&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_empty_space height=&#8221;40px&#8221;][vc_column_text]The research objective of the U-SMRC is to develop a comprehensive understanding of the biological drivers of severe schistosomal morbidity, with three specific aims:[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner gap=&#8221;15&#8243; css=&#8221;.vc_custom_1688458362744{background-color: #e9eaee !important;}&#8221;][vc_column_inner][vc_empty_space height=&#8221;80px&#8221;]<ul class=\"iconlist iconlist iconlist-icon-large \"><li ><div class=\"iconlist-item-icon\"><img src=\"https:\/\/www.muii.org.ug\/usmrc\/wp-content\/uploads\/2023\/07\/Untitled-1.png\" alt=\"Untitled-1\" \/><span class=\"shapes\"><\/span><\/div><div class=\"iconlist-item-content\">\n<h3>Human Host<\/h3>\n<p>To compare early-life Schistosoma mansoni (Sm) infection and Sm-specific immune responses between Lake Albert (LA) and Lake Victoria (LV) regions and identify co-exposures that modulate Sm-specific immune responses and morbidity risk.<\/p>\n<p><\/div><\/li><li ><div class=\"iconlist-item-icon\"><img src=\"https:\/\/www.muii.org.ug\/usmrc\/wp-content\/uploads\/2023\/07\/2.png\" alt=\"2\" \/><span class=\"shapes\"><\/span><\/div><div class=\"iconlist-item-content\">\n<h3>Parasite<\/h3>\n<p>Determine if there is a parasite genetic basis to differential Sm morbidity and establish a platform for local genetic surveillance of schistosome parasites in Uganda and determine whether there is a parasite genetic basis to differences in clinical outcomes in LA and LV.<\/div><\/li><li ><div class=\"iconlist-item-icon\"><img src=\"https:\/\/www.muii.org.ug\/usmrc\/wp-content\/uploads\/2023\/07\/3.png\" alt=\"3\" \/><span class=\"shapes\"><\/span><\/div><div class=\"iconlist-item-content\">\n<h3>Snail<\/h3>\n<p>Determine how the population biological determinants of fresh-water snail Biomphalaria spp. act as local epidemiological drivers of Sm, filtering its diversity within and between LA and LV ecosystems.<\/div><\/li><\/ul>[\/vc_column_inner][\/vc_row_inner][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space height=&#8221;40px&#8221;][vc_custom_heading text=&#8221;Partners&#8221; font_container=&#8221;tag:h3|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_raw_html]JTVCZWxmc2lnaHRfbG9nb19zaG93Y2FzZSUyMGlkJTNEJTIyMSUyMiU1RA==[\/vc_raw_html][\/vc_column][\/vc_row]<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>[vc_row full_width=&#8221;stretch_row_content_no_spaces&#8221;][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_empty_space height=&#8221;40px&#8221;][vc_custom_heading text=&#8221;Background&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_empty_space height=&#8221;40px&#8221;][\/vc_column_inner][\/vc_row_inner][vc_row_inner gap=&#8221;15&#8243;][vc_column_inner width=&#8221;1\/2&#8243;][vc_empty_space height=&#8221;10px&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_empty_space height=&#8221;30px&#8221;][vc_single_image image=&#8221;2720&#8243; img_size=&#8221;640*480&#8243;][vc_empty_space height=&#8221;30px&#8221;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1688458395547{background-color: #e9eaee !important;}&#8221;][vc_column][vc_row_inner css=&#8221;.vc_custom_1688539340866{background-color: #e9eaee !important;}&#8221;][vc_column_inner width=&#8221;1\/3&#8243;][vc_empty_space height=&#8221;40px&#8221;][vc_custom_heading text=&#8221;Specific Aims&#8221; 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